DG Peptide Protocols
Moderate ResearchLongevityImmune

Livagen

KEDA

KEDA Tetrapeptide | Liver Bioregulator

Half-life
Not established
Chain length
4 amino acids
Reference frequency
Daily for 10-20 days per cycle

Research overview

DoseGear research brief

Livagen is a Khavinson bioregulator tetrapeptide (KEDA) with significant hepatoprotective and immunomodulatory properties. Structurally similar to Epitalon, it normalizes immune and antioxidant status while restoring liver function in hepatitis conditions. Livagen is best known for its ability to decondense chromatin, activating silent genes including ribosomal genes to boost protein synthesis and cellular activity. Maximum protective effects occur during aging.

Mechanism of action

Livagen works through direct effects on DNA structure and function. It decondenses chromatin (tightly packed DNA), increasing expression of certain genes and improving the 'youthful' profile of cells. The peptide activates multiple genes in lymphocytes, including previously silent ribosomal genes, boosting protein synthesis and cell activity. It exhibits hepatoprotective effects through normalizing immune and antioxidant status in liver tissue.

Compound background

Development & research timeline

Study windows describe what researchers measured, not when an individual should expect a result.

Origin & development

Synthetic short peptide associated with Khavinson liver-bioregulator research.

What it is researched for

Experimental hepatic and chromatin regulation through proposed gene-expression effects.

Research observation window

Not reported in the reviewed compound-specific evidence.

Reference data

Lyophilized vial injectable protocols

Not personalized dosing instructions

Only injectable vial references are shown. Nasal, topical, and unsupported non-vial schedules are excluded.

Research contextAmountFrequencyRoute
Chart reference500 mcgDaily · See source guideInjectable · 20 mg lyophilized vial + 3 mL BAC Water

Reference cycle

10-20 days

Reference storage

Injectable reconstituted: 2-8°C refrigerated

Safety context

Reported side effects

  • Generally well-tolerated
  • Minimal side effects reported

Contraindications & cautions

  • Active liver emergencies (seek medical care)
  • Known hypersensitivity
  • Pregnancy or breastfeeding

Scientific references

  1. 01

    Influence of KEDA Tetrapeptide on Organism Physiological Function

    Scientific citationInfluence of KEDA Tetrapeptide on Organism Physiological Function. Advances in Gerontology (2020).
  2. 02

    Effects of Livagen Peptide on Chromatin Activation in Lymphocytes from Old People

    Scientific citationEffects of Livagen Peptide on Chromatin Activation in Lymphocytes from Old People. Bulletin of Experimental Biology and Medicine (2002).
  3. 03

    Hepatoprotective Properties of KEDA in Hepatitis Models

    Scientific citationHepatoprotective Properties of KEDA in Hepatitis Models. Experimental Biology and Medicine (2018).
  4. 04

    Khavinson Peptide Bioregulators

    Scientific citationKhavinson Peptide Bioregulators. Advances in Gerontology (2020).

This DoseGear profile combines published scientific literature with lyophilized-vial protocol references. Citations are provided for independent review.

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