DG Peptide Protocols
Well StudiedCognitiveLongevity

Cerebrolysin

Cerebrolysin®

Neuropeptide Preparation | Neurological Recovery

Half-life
Minutes (component-dependent; e.g., BDNF ~10 min)
Chain length
Variable (peptide mixture)
Reference frequency
Once daily for acute conditions; 5 days weekly for chronic conditions

Research overview

DoseGear research brief

Standardized neuropeptide preparation containing bioactive peptides and amino acids exhibiting neurotrophic and neuroprotective properties for stroke recovery, traumatic brain injury, and cognitive enhancement. Used clinically in 50+ countries.

Mechanism of action

IV/IM administration provides optimal bioavailability and brain penetration of neuropeptides and neurotrophic factors.

Compound background

Development & research timeline

Study windows describe what researchers measured, not when an individual should expect a result.

Origin & development

Standardized animal-derived peptide and amino-acid preparation, not one defined peptide.

What it is researched for

Stroke, traumatic brain injury, and dementia research with proposed neurotrophic and neuroprotective activity.

Research observation window

A cited TBI trial used an initial 10-day course plus later cycles; a dementia meta-analysis assessed outcomes at four weeks and six months.

Reference data

Lyophilized vial injectable protocols

Not personalized dosing instructions

Only injectable vial references are shown. Nasal, topical, and unsupported non-vial schedules are excluded.

Research contextAmountFrequencyRoute
Acute Stroke20-50mLOnce daily for 10-21 daysIV infusion (diluted to 100mL minimum)
Traumatic Brain Injury20-50mLOnce daily for 7-30 daysIV infusion (diluted to 100mL minimum)
Alzheimer's Disease10-30mL5 days weekly for 4 weeksIV injection/infusion (2-4 cycles yearly)
Vascular Dementia10-30mL5 days weekly for 4 weeksIV injection/infusion (2-4 cycles yearly)

Reference cycle

7-30 days depending on condition (stroke/TBI 10-30 days, dementia 4 weeks)

Reference storage

Room temperature ≤25°C, protected from light in original carton - never freeze

Safety context

Reported side effects

  • Generally well tolerated
  • Possible mild dizziness or agitation in early treatment

Contraindications & cautions

  • Epilepsy
  • Severe renal insufficiency
  • History of severe allergic reactions to porcine products

Scientific references

  1. 01

    Efficacy and Safety of Cerebrolysin in Neurorecovery After Moderate-Severe Traumatic Brain Injury: Results from the CAPTAIN II Trial

    Scientific citationEfficacy and Safety of Cerebrolysin in Neurorecovery After Moderate-Severe Traumatic Brain Injury: Results from the CAPTAIN II Trial. Neurological Sciences (2020).
  2. 02

    Safety and Efficacy of Cerebrolysin in Early Post-Stroke Recovery: A Meta-Analysis of Nine Randomized Clinical Trials

    Scientific citationSafety and Efficacy of Cerebrolysin in Early Post-Stroke Recovery: A Meta-Analysis of Nine Randomized Clinical Trials. Neurological Sciences (2018).
  3. 03

    Cerebrolysin for Functional Recovery in Patients with Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials

    Scientific citationCerebrolysin for Functional Recovery in Patients with Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials. International Journal of Neuroscience (2017).
  4. 04

    Cerebrolysin in Patients with TBI: Systematic Review and Meta-Analysis

    Scientific citationCerebrolysin in Patients with TBI: Systematic Review and Meta-Analysis. Brain Sciences (2023).

This DoseGear profile combines published scientific literature with lyophilized-vial protocol references. Citations are provided for independent review.

Related research profiles