DG Peptide Protocols
Extensively StudiedHealing & RecoveryLongevity

BPC-157

Body Protection Compound-157 | Pentadecapeptide

Half-life
<30 minutes
Chain length
15 amino acids
Reference frequency
Once or twice daily

Research overview

DoseGear research brief

Synthetic peptide derived from gastric juice protein, renowned for tissue repair, inflammation reduction, and GI protection capabilities. BPC-157 promotes blood vessel formation, enhances collagen synthesis, modulates growth factor expression, and protects against tissue damage through localized or systemic delivery.

Mechanism of action

Promotes blood vessel formation (angiogenesis), enhances collagen synthesis, modulates growth factor expression including VEGF, and protects against tissue damage through localized or systemic delivery pathways.

Compound background

Development & research timeline

Study windows describe what researchers measured, not when an individual should expect a result.

Origin & development

Synthetic pentadecapeptide associated with gastric body-protection-compound research.

What it is researched for

Predominantly animal tissue-injury, gastrointestinal, and wound-healing research; repair signaling remains proposed.

Research observation window

A cited rat muscle study followed healing for 72 days; spinal-injury research reported an outcome by day 15. These are not human recovery estimates.

Reference data

Lyophilized vial injectable protocols

Not personalized dosing instructions

Only injectable vial references are shown. Nasal, topical, and unsupported non-vial schedules are excluded.

Research contextAmountFrequencyRoute
Tendon/Joint healing250-500 mcg1-2x dailySubQ near injury
Serious injury500-1000 mcg2x dailySubQ near injury
General healing250-500 mcg1-2x dailySubQ or IM
Maintenance250 mcg1x dailySubQ

Reference cycle

4-12 weeks depending on injury

Reference storage

Lyophilized: freezer long-term; Reconstituted: 2-8°C for 4-6 weeks

Safety context

Reported side effects

  • Mild injection site redness
  • Injection site irritation

Contraindications & cautions

  • Active cancer (due to angiogenic effects)
  • Pregnancy or breastfeeding
  • Blood thinners (consult doctor due to angiogenesis)
  • WADA prohibited for competitive athletes

Scientific references

  1. 01

    Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth

    Scientific citationGastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research (2003).
  2. 02

    Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157

    Scientific citationEffective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157. Journal of Orthopaedic Research (2006).
  3. 03

    Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats

    Scientific citationStable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research (2019).
  4. 04

    BPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and Enhancing Cytoprotection

    Scientific citationBPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and Enhancing Cytoprotection. Current Pharmaceutical Design (2020).

This DoseGear profile combines published scientific literature with lyophilized-vial protocol references. Citations are provided for independent review.

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