Limited ResearchCognitive

IllumiNeuro Protocol

IllumiNeuro

Four-Peptide Cognitive Enhancement Blend

Half-life

Not reported

Chain length

Not applicable (peptide combination)

Reference frequency

Once daily, preferably in the morning for cognitive benefits

Research overview

DoseGear research brief

IllumiNeuro is a cognitive enhancement peptide blend combining four nootropic peptides: PE-22-28 (neuritogenic), Pinealon (pineal bioregulator), NA-Semax Amidate (neuroprotective/cognitive), and NA-Selank Amidate (anxiolytic/cognitive). The standard formulation contains 48mg total (PE-22-28 10mg + Pinealon 10mg + NA-Semax 20mg + NA-Selank 8mg). This blend targets multiple neurological pathways for comprehensive cognitive support, though no clinical studies exist on this specific four-peptide combination.

Mechanism of action

Each peptide contributes distinct neurological mechanisms: PE-22-28 promotes neurite outgrowth and neural connectivity through sphingosine-1-phosphate receptor modulation; Pinealon is a bioregulator that supports pineal gland function and circadian regulation; NA-Semax Amidate provides BDNF upregulation and neuroprotection; NA-Selank Amidate offers anxiolytic effects through GABA modulation and immune-neuroendocrine regulation. Together, they theoretically address cognitive enhancement, neuroprotection, mood support, and neural regeneration.

Compound background

Development & research timeline

Study windows describe what researchers measured, not when an individual should expect a result.

Origin & development

Blend of PE-22-28, Pinealon, NA-Semax Amidate, and NA-Selank Amidate; a specific developer is not established.

What it is researched for

Proposed cognition and anxiety applications based on ingredient neurotrophic, TREK-1, and regulatory hypotheses.

Research observation window

Not reported for the blend.

Reference data

Lyophilized vial injectable protocols

Not personalized dosing instructions

Only injectable vial references are shown. Nasal, topical, and unsupported non-vial schedules are excluded.

Research context	Amount	Frequency	Route
Standard protocol	200-400mcg total blend	Once daily	SubQ
Enhanced protocol	400-500mcg total blend	Once daily	SubQ

Reference cycle

4-8 weeks

Reference storage

Lyophilized: Room temperature; Reconstituted: 2-8°C, use within 4 weeks

Safety context

Reported side effects

Injection site reactions (mild)
Nasal irritation if used intranasally
Possible vivid dreams (Pinealon effect)
Mild headache initially

Contraindications & cautions

No clinical trials on four-peptide combination
Bipolar disorder or psychosis (caution with cognitive enhancers)
Pregnancy or breastfeeding
Seizure disorders (theoretical concern)

Scientific references

01
PE-22-28 Neuritogenic Effects
Scientific citationPE-22-28 Neuritogenic Effects. .
02
NA-Semax Amidate Cognitive Enhancement
Scientific citationNA-Semax Amidate Cognitive Enhancement. .
03
NA-Selank Amidate Anxiolytic Properties
Scientific citationNA-Selank Amidate Anxiolytic Properties. .
04
Pinealon Bioregulator
Scientific citationPinealon Bioregulator. .

This DoseGear profile combines published scientific literature with lyophilized-vial protocol references. Citations are provided for independent review.

Related research profiles

Cognitive