Pralmorelin
Growth Hormone Releasing Peptide-2 | Pralmorelin
DoseGear research brief
GHRP-2 is a synthetic growth hormone secretagogue that stimulates the pituitary gland to release growth hormone. It is one of the most potent members of the GHRP family, being 2-3 times more effective than GHRP-6 in stimulating GH release. Originally developed as a diagnostic agent for growth hormone deficiency, it works by mimicking ghrelin and binding to the GHS-R1a receptor.
GHRP-2 acts as a synthetic agonist of ghrelin, binding to the growth hormone secretagogue receptor (GHS-R1a) in the hypothalamus and pituitary. This stimulates cAMP production and promotes pulsatile release of endogenous growth hormone without suppressing natural feedback loops. It works synergistically with GHRH to amplify GH secretion beyond what either peptide achieves alone.
Compound background
Study windows describe what researchers measured, not when an individual should expect a result.
Synthetic growth-hormone-releasing peptide investigated diagnostically and pharmacologically.
Growth-hormone secretion and pituitary-function research through ghrelin/GHS-R1a agonism.
No sourced clinical-benefit response window is reported.
Reference data
Not personalized dosing instructions
Only injectable vial references are shown. Nasal, topical, and unsupported non-vial schedules are excluded.
| Research context | Amount | Frequency | Route |
|---|---|---|---|
| GH optimization | 100-150 mcg | 2-3x daily | SubQ |
| Enhanced results | 200-300 mcg | 2-3x daily | SubQ |
| With GHRH (synergy) | 100 mcg each | 2-3x daily | SubQ (combined) |
| Pre-sleep protocol | 100-200 mcg | Before bed | SubQ |
Reference cycle
8-12 weeks
Reference storage
2-8°C refrigerated
Growth Hormone Releasing Peptide-2 increases food intake in healthy men
Synthetic Growth Hormone-Releasing Peptides: Cytoprotective Effects
GHRP-2 effects on growth hormone release in swine
This DoseGear profile combines published scientific literature with lyophilized-vial protocol references. Citations are provided for independent review.
